Feline Infectious Peritonitis (FIP) is an unusual, but often fatal, consequence of coronavirus infection of the cat and ferret. The majority of cats and ferrets infected with coronaviruses lead perfectly normal lives. However, if you are thinking of buying a pedigree (purebred) kitten - INSIST that he or she is feline coronavirus (FCoV) free - otherwise you may be buying heartache. A paper published in Feb 2012, shows how such quarantine and testing has kept the Falkland (Malvinas) Islands free of FCoV and FIP.
Welcome to my website.
1. to provide accurate and up to date information about feline coronavirus (FCoV), the cause of feline infectious peritonitis (FIP) in cats and ferrets.
2. to provide a register of FCoV tested studs and queens so that enlightened cat breeders who know their catís FCoV status can contact each other. In the 1970s, Abysinnian cat breeders began testing for FeLV and eliminated it from their breed, other cat clubs followed suite. Now, at least in the UK, it is extremely rare for a pedigree kitten to be sold with FeLV, thanks to the dedicated testing of cat breeders. In Scotland, most Birman breeders are FCoV free. The war against coronavirus and FIP has begun - I hope you will join it.
3. to provide a register of FCoV free kittens.
4. to provide a register of stud and queen cats of known blood type.
6. to raise urgently needed funds for FIP/FCoV research.
7. to provide up to date information about feline chronic gingivostomatitis
As regular visitors to the site will know, one of my dreams is to eradicate FCoV, and therefore FIP, from the whole world! Some years ago, the veterinary surgeons on the Falklands Islands, suspecting that the cats who lived there were already FCoV free, instituted a policy where all cats being imported to the Islands had to test negative for antibodies to Feline Coronavirus, the virus which cases Feline Infectious Peritonitis (FIP). We have just published a paper in the Journal of Feline Medicine and Surgery (JFMS), the journal of the International Society of Feline Medicine, showing that this policy was effective. [The second piece of exciting news on this is that Sage have just taken over JFMS and have made the February 2012 edition free to access, following the link below.]
On a smaller scale, you can keep the cats in your household FCoV free (and therefore FIP free) by testing new incoming cats and kittens for FCoV antibodies BEFORE bringing them into the house. Too often I hear sad tales of an existing pet developing FIP after the introduction of a cat or kitten from a high-risk source, such as a breeder or rescue shelter. There are good breeders out there producing FCoV-free kittens - be sure to demand a FCoV antibody test before purchase. If the test turns out to be positive, then one can test the faeces to determine whether the cat is actually shedding virus, and if so, wait 2-3 months and re-test if you're keen to have that particular cat (or rehome the cat to somebody with no other cats).
I was proud to be invited to contribute to the Fourth Edition of Prof. Craig Greene's legendary textbook "Infectious Diseases of the Dog and Cat." For me, this is the Bible of canine and feline infectious disease. It is available from Amazon. [Note - it is for veterinary surgeons only.]
""Feline Infectious Peritonitis and Coronavirus" - download an ebook written for cat guardians or purchase the physical version from Amazon.
The chapters are:
1. Everything you need to know when your cat has been diagnosed with FIP
........(This download will open up in a new page as a word document.)
2. Everything you need to know about treating a cat with FIP
...... Download a current FIP treatment sheet from the Downloads menu to take with you to your veterinary surgeon.
3. Preventing your other cats or kittens from developing FIP
4. Everything you need to know about getting another cat or kitten
5. Everything you need to know if your cat or kitten is diagnosed as having diarrhoea caused by FCoV
6. Everything you need to know if you work in a rescue shelter or boarding cattery
7. FCoV/FIP prevention in trap, neuter, return (TNR) programs
8. Everything you need to know if you keep a lot (over 6) pet cats, or have a cat sanctuary or colony
9. Everything you need to know if you are a cat breeder
10. What you can do to help fight FIP
11. Everything you need to know to find more information
When I began this website, FIP was incurable. Now, with the introduction of feline interferon omega (Virbagen Omega by Virbac) into some of Europe we are seeing some cases enter remission and others being cured. In summer of 2009, an exciting paper appeared by Prof. Al Legendre of Tennessee Veterinary School in the Journal of Feline Medicine and Surgery reporting cure of 3 cases of non-effusive FIP using Polyprenyl Immunostimulant from Sass & Sass. This paper is a hopeful pilot study and I look forward to a controlled clinical study. Unfortunately, Polyprenyl Immunostimulant does not work on effusive (wet) FIP cases.
My dream is for no cat ever to contract FIP in the first place, never mind die of it.
For more on FIP treatment - visit my FIP treatment webpage. The search for a cure is hampered by lack of funds, if you would like to donate to FIP research, you can do so on this website.
I am happy to announce the launch of a You Tube channel dealing primarily with Feline Infectious Peritonitis and Feline Chronic Gingivostomatitis, but also including other items of animal welfare. I am deeply grateul to talented French veterinary animator Dr Francois Bagaini of Vetocyte.fr for bringing some of my ideas to life.
To visit the channel, go to You Tube.
Here is our most recent video:
Please press the thumbs up "like" button to support our videos.
(This section is written for veterinarians.)
It has been known for a while that ferrets had a unique coronavirus of their own (ferret enteric coronavirus, FECV) which causes epizootic catarrhal enteritis [3,4]. They also suffer from a disease which looks very much like infectious peritonitis of cats [1,2] and I am most grateful to Dr Jerry Murray, a ferret expert in Dallas, Texas, for bringing this to my attention.
Reported clinical signs include anorexia, weight loss, diarrhoea, large palpable abdominal masses. Effusions have not been described. Antibody against feline infectious peritonitis virus can be used in immunohistochemistry to confirm diagnosis.
At present moment, treatment is similar to that of FIP in cats - prednisolone. It is unknown whether interferon would help these ferrets or whether Primucell vaccination (Pfizer) would be effective in preventing it, though there is no reason to suppose it would not be protective (however, it would be used off-licence).
1. Juan-Salles C, Teifke JP, Morera N, Jiminez J, Montesinos A, Ardiaca M, Loehr CV, Garner MM. 2006 Pathology and immunohistochemistry of a disease resembling feline infectious peritonitis in ferrets (Mustela Putorius Furo). Vet Pathol 43:5 p845
3. Williams BH, Kiupel M, West KH, Raymond JT, Grant CK, Glickman LT. 2000 Coronavirus-associated epizootic catarrhal enteritis in ferrets. J Am Vet Med Assoc 217(4):526-30.
4. Wise AG, Kiupel M, Maes RK. 2006 Molecular characterization of a novel coronavirus associated with epizootic catarrhal enteritis (ECE) in ferrets. Virology. 349(1):164-74.
If you have a cat suffering from chronic gingivostomatitis (FGS) and would like to help in research, please download 2 questionnaires and take them to your veterinary surgeon to complete with you - one is for the cat with FGS and the other is for a cat without FGS (we call this a "control" - it is an extremely important part of the study). This research is based at the University of Glasgow Veterinary School in Scotland but we are pleased to hear from cases from anywhere in the world. The aim of this research is to further clarify the causes of FGS which will help in our search for a cure.
Tuscany, Italy . Sunday 23rd June 2013.
To book a place, contact Dr Francesca Serena, f.serena @ usl11.toscana.it
Madrid, Spain, 2010
This highly successful event sold out with over 150 delegates attending - I'm sorry if you tried to attend and were not able to. However, the proceedings are available (in English and Spanish, to veterinary surgeons only), though I believe you have to order a quantity of Purevax vaccine in order to get a free copy of the proceedings. Please contact Dr Daniel Rodes, of Merial, Spain - Daniel.RODES@Merial.com - to find out how to obtain a copy.
The author: Dr Diane D Addie
Dr Diane D Addie is a veterinay surgeon and virologist who has spent the last 23 years researching feline infectious peritonitis (FIP) and feline coronavirus infection (FCoV). She qualified as a veterinary surgeon from the University of Glasgow, in Scotland, and spent 8 years in small animal practice in the north of England. She returned to Glasgow Veterinary School to research into FIP, her PhD was entitled "Studies on the humoral immune response to feline coronavirus." She is Honorary Senior Research Fellow at the University of Glasgow, Scotland, U.K and Director of the Feline Institute Pyrenees in France. Dr Addie serves on the European Advisory Board of Cat Disease.
Her dream is to eradicate FIP, at least from pedigree/purebred cats, and preferably also from rescue shelters, within the next 10 years. By becoming informed and spreading reliable knowledge, or by fundraising for research you can help her fight FIP.
She takes the stand that she prefers not to experiment on animals and all her studies have been on animals who have become infected or sick naturally and whose veterinary surgeons or guardians have contacted her.
In 2003 she received the Amoroso award for for outstanding contributions to small animal studies by a non-clinical member of university staff. She served on the council of Cats Protection for 20 years and is currently a patron of the Celia Hammond Animal Trust.
Declaration of lack of vested interests
The opinions and recommendations given on this website are completely independent - Dr Addie is not in on the payroll of any corporation, nor does she hold shares in any company mentioned on this site, nor is she on any board of directors of any corporation or company whose products are mentioned on this site, with the exception of the ebooks for sale on this site, where she receives up to 65% of the income, this being her main source of income. Dr Addie takes no income from donations made to the Angelica Trust.
She is a member of the European Advisory Board of Cat Disease whose meetings are funded by Merial, but whose veterinary members are volunteer and are unpaid. Merial simply pays the travel expenses and hotel.
Your use of this website at your own risk. This site is for information purposes only and is in no way intended to replace a consultation with a fully qualified veterinary surgeon (veterinarian). The information in this site cannot and should not be used as a basis for diagnosis or choice of treatment. Dr Addie excludes all liability whatsoever for any loss or damage arising out of use of this site or reliance upon its contents and strongly advises all users with veterinary related queries to consult a veterinary surgeon.
Dr Diane D. Addie is available for consultations for infectious disease control or diagnosis to veterinary hospitals, rescue shelters, boarding and breeding catteries and industry. She is also available to laboratories for consultation for the development of diagnostic tests. For private, individual, consultation regarding your own pet, you must obtain the permission of your veterinary surgeon in writing for me to consult with you before you contact me (these are the rules of the Royal College of Veterinary Surgeons). Email: draddie @ btinternet.com.
The web designer: Melody Amundson
Melody Amundson of Mariposa Creations made this site possible by generously offering her fantastic web designing skills free of charge as her generous donation to the cause of fighting Feline Infectious Peritonitis. She has given of her time and skills for over 8 years to keep this website working! You can see how artistic she is from the beauty of this website and the Orion Foundation website, and another example is her lovely colouring book for children, which you can purchase from her Devon Heaven website. Melody is a breeder of Devon Rex kittens and is active in the cat show world in the USA. She also forays into the world of cat rescue and any cat who crosses her path will benefit from the encounter!
The translator:Renata Fernandes
Renata Fernandes of rftranslations arranged translations of the site into other languages. Each language had 4 translators working on the website's text plus a proofreader at the end. Over 30 people from different parts of the world were willing to help get rid of coronavirus by using their translating skills and did so ENTIRELY VOLUNTARILY! This was an astonishing donation to help spread the word on FIP!
Renata has her own animal website AnimalSofties.com.
Unfortunately I am unable to answer all the queries that come to my inbox. I'm very sorry, but I'm sure you'll appreciate that every moment spent responding to queries is a moment less to devote to research. In addition, it would be unethical for me to advise another veterinary surgeon's client without their consent. Time permitting, if you donate to FIP research and provide written consent for me to respond to you from your veterinary surgeon, I will try to answer some queries. Go to the Angelica Memorial Page to make a donation.
Forums and chat groups provide support and answer queries for people with a cat suspected of having FIP or for those who are unfortunate enough to have lost a cat to FIP. These are two that I personally recommend:
The site is continually being updated and new material added. I hope that you will find the answer to your questions here and that youíll come back soon.
"The light shines in the darkness, and the darkness could not put it out."
you and your cats!
Last updated 1 May 2013
If you'd like to put a graphic link to us on your site, please use this banner with the link: http://www.dr-addie.com Thank you!
2000-2013 Dr. Diane Addie